Complement Component C5a Mediates Hemorrhage-Induced Intestinal Damage
نویسندگان
چکیده
منابع مشابه
Complement component C5a mediates hemorrhage-induced intestinal damage.
BACKGROUND Complement has been implicated in the pathogenesis of intestinal damage and inflammation in multiple animal models. Although the exact mechanism is unknown, inhibition of complement prevents hemodynamic alterations in hemorrhage. MATERIALS AND METHODS C57Bl/6, complement 5 deficient (C5-/-) and sufficient (C5+/+) mice were subjected to 25% blood loss. In some cases, C57Bl/6 mice we...
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ژورنال
عنوان ژورنال: Journal of Surgical Research
سال: 2008
ISSN: 0022-4804
DOI: 10.1016/j.jss.2008.02.010